Thursday, December 27, 2018
'DNA the Master Code for All Living Things\r'
'Bacteria, zebras, mosquitoes, anacondas, essenti solelyy all living liai tidingss energise better halfless thing in common which makes them what they atomic number 18. It is deoxyribonucleic acid. It is one of the superior biological failies in the history of mankind. It is not whole related to biology just now is tied to the direct of chemistry as well be safari of the convoluted molecular coordinate. desoxyribonucleic acid is short for the scintilla deoxyribonucleic acid. RNA or ribonucleic acid is another nucleic acid derived from deoxyribonucleic acid and utilize as a usher to make proteins, the product of the transmittable enactment.\r\nIn an name, ââ¬Å"What is deoxyribonucleic acid? ââ¬Â written by crowd together Randerson, deoxyribonucleic acid is described as, ââ¬Å"ââ¬Â¦ he conquer code for carriage ââ¬Â¦ the instruction view as that severally organism uses to run its automobile trunk and govern its behavior, a nurse that each creature hands on to its offspring, either in full or in part. ââ¬Â In other words it describes how at times not the whole book ( deoxyribonucleic acid) is passed d proclaim from p arnt to progeny. A contract and mother ii contri besidese their deoxyribonucleic acid making the son similar however not identical to his father and mother. Also, because deoxyribonucleic acid stores all genetical in constructation including diseases, which backside be passed waste from generation to generation. These diseases argon the effect of a mutation in the desoxyribonucleic acid social structure.\r\nIn 1868, a Swiss physician and biologist extracted a atomic number 15 containing ticker. He called it nuclein because he found it in the nuclei of several mobile phones. He managed to extract this substance from discarded surgical bandages, specifically by examining the pus cells (pus cells atomic number 18 white caudex cells). James Watson, an American geneticist, and Francis haystack, a British physicist studying in the University of Cambridge, began examining x-ray images do by Rosalind Franklin and Maurice Wilkins. In 1953, James and Francis constructed the first of all three-dimensional sit around of the desoxyribonucleic acid structure.\r\nThe model showed all nitrogen-bearing menials, pentoses (sugar), and inorganic phosphate groups. some(prenominal) years later, James Watson, Francis Crick, and Maurice Wilkins received the Nobel calculate for Physiology or Medicine. Before the three-dimensional model, Erwin Chargaff notice a pattern surrounded by the composition pairs. He discovered that the amount of antiophthalmic factor is the resembling amount of thymine. the same is unbent for the other make pair one thousand and cytosine. Chargaffââ¬â¢s discovery led him to figure the basic pairing rules. You might appreciation what makes our desoxyribonucleic acid antithetic from the deoxyribonucleic acid of a sheep, sea urchin, or a turtle.\r\n gr ound on the studies of Chargaff and the rest of his colleagues at capital of South Carolina University, the four nitrogenous miserlys occur in different ratios in the deoxyribonucleic acids of different organisms and that the launchs reserve a numerical relationship. For example, The understructure piece of music (mol percentage) of Homo Sapiens is 30. 9 % adenine, 19. 9% grand, 19. 8% cytosine, and 29. 4% thymine. This shows that Chargaffââ¬â¢s study was very attend toful for James Watson and Francis Crickââ¬â¢s three-dimensional model of a desoxyribonucleic acid molecule. I chose to research desoxyribonucleic acid because it is a very interesting melodic theme to discuss.\r\nIt makes me who I am, my hair, eye, and skin color, my height and weight, general health, metabolism, etc. I find both biology and chemistry my favorite subjects and deoxyribonucleic acid because it is a key molecuel that defines health. In the approaching I plan to become a M. D. (Medical D octor). I will definitely have to be familiar with this molecule and what deoxyribonucleic acid sequences mean in case I needed to diagnose a patient with a certain genetic disease. By examining his or her genetic code I could determine possible diseases. I truly enjoy any type of chore solving. I could utilize this knowledge to search disease in my own family, specifically my dadaââ¬â¢s side.\r\nFrom my grandfather to my own father and uncles, everyone has minor cardiovascular diseases caused by high cholesterol. I want to discover what mutation in my familyââ¬â¢s DNA that causes this condition and develop treatments to improve their health. DNA molecules are located in the cell nub of a cell. When they are tightly packed together they are known as chromosomes. The structure of DNA is very complicated. DNA is a double helix molecule. The structure estimates like a twisted ladder. A double helix is the molecular structure created from double-stranded molecules of nuc leic acids held together by hy drogen bonding between nucleotides.\r\nNucleotides contain three characteristic components: (1) a nitrogenous base, (2) a pentose (sugar), and (3) phosphate group. 4 nitrogenous bases make up DNAs stand of the double helix: adenine (A), gigabyte (G), cytosine (C), and thymine (T). These bases are pause into two groups. (A) and (G) are in the purine base group and (C) and (T) are in the pyrimidine base groups. In the structure of DNA base pairs are unioni set between the four bases. A base pair is when two nitrogenous bases (a purine to a pyrimidine or feebleness versa) are linked by lightsome heat content bonds.\r\nAdenine (A) and thymine (T) form a base pair and guanine (G) and cytosine C) form a base pair. In the structure of DNA (A) and (T) are held together by two hydrogen bonds, while (C) and (G) are held together by three hydrogen bonds. The next components of DNA form the backbone of the two verticillate strands. The backbones consist of alternating phosphate and pentose (sugar). 2 kinds of pentoses are found in nucleic acids, deoxyribose and ribose. Deoxyribose is essentially the same as ribose but it has one less oxygen atom in itââ¬â¢s structure. The phosphate group is machine-accessible to the pentose (deoxyribose or ribose) on the backbone of the DNA structure.\r\nThey are both held together by covalent bonds. The pentose is also connected to the nitrogenous base. When a pentose (sugar) and a base flow it is called a nucleoside. An example of a nucleoside, is when the base thymine bonds with the pentose (sugar) deoxyribose, deoxythymidine forms. The nucleoside then combines with the phosphate to make the nucleoside a nucleotide. In the article ââ¬Å"How DNA Works,ââ¬Â Craig Freudenrich explains how the ââ¬Å"hydrogen bonds between phosphates cause the DNA strand to twist.\r\nThe nitrogenous bases level off inward on the ladder and form pairs with bases on the other side. This makes DNA look somewh at like a gyrate staircase. DNA functions to store the complete genetic information required to specify the structure of all the proteins of each species of organism, to program in time and space the orderly biosynthesis (the process of converting simple nutrients like: sugars, lipids, and aminic acids into complex products like, proteins and vitamins) that make cell and tissue, and organs which determine the activities of an organism throughout its life cycle, and determine the distinctiveness of the given organism.\r\nDNA also has another function. It is meant to be replicated so copies can be passed down from cell to cell and generation to generation. The National gentlemans gentlemanity Genome explore Institute describes the transfer occurs ââ¬Å"In informal reproduction, organisms inherit half(prenominal) of their atomic DNA from the male parent and half from the female parent. However, organisms inherit all of their mitochondrial DNA from the mother. This occurs bec ause only egg cells, and not sperm cells, keep their mitochondria during fertilization.\r\nTo complete these instructions, DNA sequences are transcribed into messages made of RNA and at last translated into sequences of amino group acids to produce proteins. DNA genetic information is composed of specific ache sequences of A, T, G, and C. The process begins with the sequences being transferred to a iodine strand RNA molecule. RNA is only slightly different from DNA. The important inequality between them is that one of the pyrimidine bases are not the same. Thymine is a principal(prenominal) pyrimidine in DNA, while uracil is a principal pyrimidine in RNA.\r\nThe new RNA (mRNA) molecule is a messenger containing transcribed code from the DNA molecule. The mRNA travels out of the nucleus into the cytoplasm. According to The National Human Genome Research Institute, in the cytoplasm ââ¬Å"the information contained in the mRNA molecule is translated into the ââ¬Å"languageâ⬠ of amino acids, which are the building blocks of proteins. This language tells the cells protein-making machinery the minute order in which to link the amino acids to produce a specific protein.\r\nThis is a major task because there are 20 types of amino acids, which can be placed in many another(prenominal) different orders to form a wide variety show of proteins. ââ¬Â Proteins do around of the work in our bodies; they move molecules in our bodies, they help us move by making our muscles, they help create our immune system that helps nourish from any infections in our body or illnesses, and much more. DNA is one of the greatest discoveries my man. It was not discovered by a single human being but several. DNA is what makes a female human to give birth to a bodge girl not to a tike giraffe or cub.\r\nDNA is passed down from generation to generation by sexual reproduction. Half of the fatherââ¬â¢s genes and half of the motherââ¬â¢s go to their son or daughter. Your DNA is not the same as your brotherââ¬â¢s because sometimes you get more from your momââ¬â¢s side or more from your dadââ¬â¢s side, it all depends. It is extraordinary how we are made from a string of DNA molecules that construct our body and make us who we are. DNA is now at a point where we use it for many reasons, not just for research. DNA forensics is one of the most practical ways of using DNA.\r\nForensics is the lotion of many sciences to discover aspects about a offence. A government website describing DNA forensics, lists many examples of DNA uses for Forensic Identification. They include: ââ¬Å" appointment of potential suspects whose DNA may match evidence left at crime scenes; exoneration of persons wrongly accused of crimes; realization of crime and catastrophe victims; establishment of fatherhood and other family relationships; identification of endangered and protected species as an aid to wildlife officials (could be used for prosecuting poachers); de tection of acteria and other organisms that may dirty air, water, soil, and food; Matching organ donors with recipients in transplant programs; determination of pedigree for seed or livestock breeds; and authentication of consumables much(prenominal) as caviar and wine. ââ¬Â It is great that DNA has been incorporated into forensics. Hopefully, in the near future, DNA technologies will be incorporated in a variety of other applications.\r\n'
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